Cefepime-Induced Encephalopathy: A Possible Additional Mechanism of Neurotoxicity
نویسندگان
چکیده
منابع مشابه
Cefepime-induced encephalopathy
Accepted 3 January 2018 DesCripTion A 61-year-old man has been unable to leave his bed since being diagnosed with cerebral palsy at the age of 2 years. He is fed via a gastrostoma and has previously contracted aspiration pneumonitis three times. He has had no history of seizures or myoclonic movements until the time of hospitalisation. He visited a physician with complaints of fever lasting for...
متن کاملCefepime-induced encephalopathy with normal renal function
Cefepime is a fourth-generation cephalosporin that is frequently used in a wide array of infections. Since approval for use, concerns have been raised due to adverse effects including seizures, encephalopathy and myoclonus especially if renal dysfunction is present. Despite having appropriate renal dose adjustments, cases have been found with adverse neurological effects. On this occasion, we p...
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We present here a case of 58-year-old male operated for coronary artery bypass graft surgery with four grafts. He developed neurologic symptoms with injection cefepime which recovered after withdrawal of the drug.
متن کاملCefepime neurotoxicity in the intensive care unit: a cause of severe, underappreciated encephalopathy
INTRODUCTION Cefepime, a broad spectrum antibiotic, is commonly prescribed in intensive care units (ICU) and may be an overlooked cause of neurologic symptoms such as encephalopathy, myoclonus, seizures, and coma. We aimed to characterize cefepime neurotoxicity in the ICU. METHODS We performed a retrospective study of adult ICU patients treated with intravenous cefepime for at least 3 days be...
متن کاملCharacterizing Cefepime Neurotoxicity: A Systematic Review
Neurotoxicity due to cefepime has not been well characterized. We performed a systematic review of the literature and included 5 additional cases from our center. Of the 198 cases found, the mean age was 67 years and 87% of patients had renal dysfunction. The most common clinical features were diminished level of consciousness (80%), disorientation/agitation (47%), and myoclonus (40%). It is wo...
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ژورنال
عنوان ژورنال: Neurocritical Care
سال: 2020
ISSN: 1541-6933,1556-0961
DOI: 10.1007/s12028-019-00894-2